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Research leading up to the discovery of insulin revealed connections between the pancreas and diabetes, highlighting insulin's role in treating the disease. However, the recognition of type 2 diabetes in 1936 showed that insulin was not the optimal treatment for all forms of the disease, prompting the search for other therapeutic agents.
The development of diabetes medications has been diverse and often surprising. From clinical serendipity to scientific design, sulfonylureas emerged from the use of antibiotics prone to causing hypoglycemia, while biguanides were initially used despite their known hypoglycemic properties. Other medications, such as alpha-glucosidase inhibitors and thiazolidinediones, originated from compound screening programs. These advances have expanded therapeutic options for diabetes, providing hope for those living with the disease.
Discover the origins and evolution of diabetes treatments by reading this full article in our Gaffel News Magazine: https://www.flipsnack.com/CCA6559BDC9/gaffel-news-edici-n-21-febrero-2024/full-view.html
Source: https://bjd-abcd.com/index.php/bjd/article/view/1003/1239
